Wednesday, July 01, 2020

Infectious Diseases among Older Adults: Perspectives of a Microbiologist


Infectious Diseases among Older Adults: Perspectives of a Microbiologist

By the year 2050, individuals over the age of 65 will represent 20 percent of the United States population (Ortman, Velkoff, & Hogan, 2014). As the population increasingly ages, the U.S healthcare system will continue to feel the burden of this vulnerable age group. As a microbiologist, I have learned to appreciate that the diagnosis of infectious diseases in the elderly can prove to be rather challenging. In turn, any delay in the treatment of these infections can result in an increased incidence of morbidities and mortality for this demographic. To make matters worse, the elderly are especially vulnerable and at an increased risk of acquiring these infections.

There are several reasons why the geriatric population tends to be more prone to infectious diseases. As people age, it becomes more common for these patients to suffer from multiple chronic conditions which can predispose them to infections. Older adults also have a diminished immune system which prevents the body from mounting the response necessary to fight off infection (Yoshikawa, 2000). In addition to a weakened immune response, certain factors such as the thinning of skin, stretching of the urothelium, and a decline in mucociliary clearance can disrupt the natural barriers meant to protect an individual from infections (Boling, Hobgood, & Chandekar, 2017). Frailty and cognitive impairments are risk factors that decrease an older patient’s ability to get around and maintain personal hygiene. Malnutrition and adverse drug interactions can impact the overall wellness of these individuals leading to even more risk of infections (Kaye, 2011).

Geriatric patients typically do not present to clinicians with the usual signs and symptoms of infection contributing to further delays in diagnosis and treatment. Fever and increased white blood cell count are symptoms that may not occur in the elderly but are often seen in younger patients. For many of these patients, the only sign of infection is cognitive impairment or confusion which can easily be dismissed as a normal part of the aging process. Because older patients manifest in atypical ways, clinicians need to familiarize themselves with these nonspecific presentations. Symptoms such as anorexia, weakness, urinary retention, and weight loss may be the only signs of
the presence of an infectious disease in the elderly (Boling et al, 2017). Clinicians need to spend more time with their older patients and perform a thorough assessment including an interview of family members in order to better identify those at risk for infections (Mouton et al, 2011). Educational opportunities and workshops focusing on geriatric care would be beneficial to providers who will continue to see older patients as these Baby Boomers continue to age.

In addition to diagnostic challenges, the treatment of infectious diseases has also proven to be problematic for clinicians. The recent increase in drug-resistant bacteria has especially affected this age group due to their increased exposure to these organisms in hospitals or long-term healthcare facilities. These bacteria can colonize patients and be spread from person-to-person creating an increased risk for active infections. Infection control processes, such as hand hygiene and proper PPE, can help to combat the spread of these organisms and further protect the elderly; a point which has become glaringly obvious with the current COVID-19 pandemic. I feel the transmission of infectious diseases can be decreased by focusing on public health policies for the elderly and increasing vaccination availability. In order to help protect the elderly from COVID-19, it is critical that a vaccine be developed. Unfortunately, this is not an easy task and side effects including effectiveness of the vaccine need to be considered before distribution.

References:

Boling, P., Hobgood, S., & Chandekar, R. (2017). Hospital infection control: geriatrics unit. Retrieved from
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Kaye, K.S. (2011). Comorbidities, metabolic changes make elderly more susceptible to infection. Retrieved from


Mouton, C.P., Bazaldua, O.V., Pierce, B., & Espino, D.V. (2015). Common infections in older adults. Retrieved from


Ortman, J.M., Velkoff, V.A., & Hogan, H. (2014). An aging nation: the older population in the United States. Retrieved from  https://www.census.gov/prod/2014pubs/p25-1140.pdf

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